R & D

The main aim of the Aion R&D Centers is to design, develop and optimize commercially viable synthetic processes for APIs and Intermediates of Generics and customer's discovery products. Aion Pharma has Two Research & Development facilities. The main R&D Center is at Hyderabad, working round the clock which was originally started as Aion Research Center (ARC) in Hyderabad and has a team of high caliber scientists.

Autoclaves and hydrogenators are available for conducting high temperature and high-pressure experimental reactions. The Centers have state-of-the-art instruments like automated multifunctional reaction systems, an analytical laboratory and a library with 24 hours internet access. Aion R&D has evaluated more than 500 product opportunities and developed processes for more than 200 products, out of which 80 are already at commercial scale.

Apart from the above, each plant has its own R&D center.

Besides the required infrastructure, the Hyderabad plant's R&D center has a Pilot Plant for scale-up studies, various materials of construction comprising 44 reactors of from 100 to 2000 Lt. capacity various materials of construction. All Two Research facilities are inspected and certified as per ISO 9000 standards.

Hyderabad plant R&D centre has the GMP Kilo lab having 5 all glass reaction units from 20 lts to 100 lts and all the necessary equipment to make API under GMP.

Chemical Hazard evaluation lab is attached to R&D at Hyderabad facility to conduct reaction calorimetry and is run by group of chemical Engineers and chemists. All the processes are evaluated and necessary recommendations are given to run the process commercially.

There is a pool of more than 250 scientists working in all the Two research centers. Both ARC-Hyderabad and ARC-Vizag have been recognized by the Department of Science & Technology of Govt. of India, as industry research centers. The ARC-HYD centre is also recognized by a few universities for doctoral work.

Broad areas of engagement of the Research Centers:

• Development of alternative routes of synthesis to achieve patent non- infringement.
• Study and development of less hazardous and safer process, avoiding corrosive and harmful reagents, solvents, process conditions etc.
• Development of environment friendly effluent and/or waste by products.
• Attempts to recycle by products and achieve zero waste output.
• Achieve higher quality product.
• Optimizing production efficiency and economy of scale without sacrificing quality.

R&D Units also carry out Process Justification, Cleaning Procedures, Specification Development, Analytical Method Development, Rework Procedures, Validation Studies, Stability Studies and Investigations.